Jagged 2 Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
Synonyms
D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.
Gene ID
3714
Swiss Prot
Q9Y219
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
201-300/1238
Target
Jagged 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human Jagged 2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
There is a chance that this protein will cross-react with JAG1 based on 77% sequence similarity
Gene ID URL
3714
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig
Curated Selection
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