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BMPR2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

Synonyms

BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II; Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR2

Gene ID

659

Swiss Prot

Q13873

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

921-1038/1038

Target

BMPR2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human BMPR2

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

659

Predicted Cross Reactivity

Human, Rat, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

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