ZDHHC21 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity) .
Synonyms
DNZ1; DHHC21; DHHC-21; HSPC097; 9130404H11Rik; Palmitoyltransferase ZDHHC21; Zinc finger DHHC domain-containing protein 21; ZDHHC21
Gene ID
340481
Swiss Prot
Q8IVQ6
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
131-240/265
Target
ZDHHC21
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human ZDHHC21
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
340481
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Horse, Rabbit
Curated Selection
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