Sin3b Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Synonyms
SIN3 homolog B transcription regulator; Transcriptional corepressor Sin3b; SIN3B_HUMAN.
Gene ID
23309
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
261-360/1162
Target
Sin3b
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Sin3b
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23309
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken
Curated Selection
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