Sin3b Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

Synonyms

SIN3 homolog B transcription regulator; Transcriptional corepressor Sin3b; SIN3B_HUMAN.

Gene ID

23309

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

261-360/1162

Target

Sin3b

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human Sin3b

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23309

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken

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