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IL-18 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

Synonyms

Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN; IL18_RAT; IL18_MOUSE.

Gene ID

29197

Swiss Prot

P97636

Host

Rabbit

Cross Reactivity

Rat

Target

IL-18

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

Recombinant rat IL-18 protein

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1mg/ml

Dilution

IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

29197

Predicted Cross Reactivity

Mouse

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