LARG Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Product Specifications
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia (from EntrezGene) . LARG has also been implicated in linking heterotrimeric G proteins to microtubule organisation in regulation of cell polarity.
Synonyms
ARHGEF12; KIAA0382; leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; PRO2792; Rho guanine exchange factor GEF 12; Rho guanine nucleotide exchange factor GEF 12; Rho guanine nucleotide exchange factor 12; Similar to Mouse Lsc oncogene; ARHGC_HUMAN.
Gene ID
23365
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
515-615/1544
Target
LARG
Clonality
Polyclonal
Isotype
IgG
Conjugation
PerCP-Cy5.5
Source
KLH conjugated synthetic peptide derived from human LARG
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
482nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23365
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6327909-01 0.2 mL
OR10AG1, CT (OR10AG1, Olfactory receptor 10AG1, Olfactory receptor OR11-160) (AP)
Ask
View Details MBS6327909-02 5x 0.2 mL
OR10AG1, CT (OR10AG1, Olfactory receptor 10AG1, Olfactory receptor OR11-160) (AP)
Ask
View Details 11152023 100 PCS
MCE Membrane Filter, Black, Gridded, Sterile, Individual Packed, 0.45 (μm), 25 (mm), 100pcs/pk
Ask
View Details