LARG Polyclonal Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia (from EntrezGene) . LARG has also been implicated in linking heterotrimeric G proteins to microtubule organisation in regulation of cell polarity.
Synonyms
ARHGEF12; KIAA0382; leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; PRO2792; Rho guanine exchange factor GEF 12; Rho guanine nucleotide exchange factor GEF 12; Rho guanine nucleotide exchange factor 12; Similar to Mouse Lsc oncogene; ARHGC_HUMAN.
Gene ID
23365
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
515-615/1544
Target
LARG
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5.5
Source
KLH conjugated synthetic peptide derived from human LARG
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23365
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
Curated Selection
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