LARG Polyclonal Antibody
Product Specifications
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia (from EntrezGene) . LARG has also been implicated in linking heterotrimeric G proteins to microtubule organisation in regulation of cell polarity.
Synonyms
ARHGEF12; KIAA0382; leukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; PRO2792; Rho guanine exchange factor GEF 12; Rho guanine nucleotide exchange factor GEF 12; Rho guanine nucleotide exchange factor 12; Similar to Mouse Lsc oncogene; ARHGC_HUMAN.
Gene ID
23365
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
515-615/1544
Target
LARG
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LARG
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
23365
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
Curated Selection
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