DMBT1 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
DMBT 1 may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. [Subcellular Location] Secreted. Membrane. [Tissue Specificity] Expressed in von Ebner glands (VEG) (at protein level), olfactory epithelium and the lateral nasal gland. Expressed in transit-amplifying ductular (oval) cells. Up-regulated at day 3 after hepatectomy. Expressed in newly formed bile ducts and in structures resembling intestinal epithelium. Belongs to the DMBT1 family.
Synonyms
GP340; Apactin; CRP; CRP-[a]; CRP-[b]; CRP-ductin; Crpd; DBMT1; Deleted in malignant brain tumors 1; Deleted in malignant brain tumors 1 protein; DMBT 1; DMBT1 prototype precursor; DMBT1/6kb.1 protein precursor; DMBT1/8kb.1 protein; DMBT1/8kb.2 protein precursor; Ebnerin; Glycoprotein 300; Glycoprotein 340; Gp 340; gp300; Gp340 variant protein; Hensin; Mucin-like glycoprotein; Muclin; p80; Pancrin; Salivary agglutinin; Surfactant pulmonary associated D binding protein; Surfactant pulmonary associated protein D binding protein; Vomeroglandin.
Gene ID
1755
Swiss Prot
Q9UGM3
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
215-420/2085
Target
DMBT1
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
Recombinant mouse DMBT1 protein
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1755
Predicted Cross Reactivity
Rat
Curated Selection
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