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TNFRSF10A Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

Synonyms

TR10A_HUMAN; Tumor necrosis factor receptor superfamily member 10A; APO2; DR4; TRAILR1; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1 (TRAIL receptor 1; TRAIL-R1) ; CD261

Gene ID

8797

Swiss Prot

O00220

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

288-468/468

Target

TNFRSF10A

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

Recombinant human DR4 protein

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8797

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