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POLK Polyclonal Antibody, Cy5.5 Conjugated

Product Specifications

Background

This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]

Synonyms

DINP; POLQ; DINB1; DNA polymerase kappa; DINB protein; POLK_HUMAN.

Gene ID

51426

Swiss Prot

Q9UBT6

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

1-472/870

Target

POLK

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5.5

Source

Recombinant human POLK protein

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

1µg/µl

Dilution

IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51426

Predicted Cross Reactivity

Mouse

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