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MAPK11 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Synonyms

P38B; SAPK2; p38-2; PRKM11; SAPK2B; p38Beta; P38BETA2; Mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; Mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; Stress-activated protein kinase 2b; MAPK11

Gene ID

5600

Swiss Prot

Q15759

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

21-120/384

Target

MAPK11

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human MAPK11

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5600

Predicted Cross Reactivity

Mouse, Dog, Horse

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