TLR7 Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Synonyms
TLR-7; PRO285; TLR 7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248.
Gene ID
51284
Swiss Prot
Q9NYK1
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Target
TLR7
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
Recombinant human TLR7 protein
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
51284
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