LATS2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
Synonyms
Serine/threonine-protein kinase LATS1; LATS1; Large tumor suppressor homolog 1; WARTS protein kinase; h-warts; WARTS; Serine/threonine-protein kinase LATS2; LATS2; Kinase phosphorylated during mitosis protein; Large tumor suppressor homolog 2; Serine/threonine-protein kinase kpm; Warts-like kinase; KPM
Gene ID
26524, 9113
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
641-740/1088
Target
LATS2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LATS2
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This antibody will detects both LATS1 and LATS2.
Gene ID URL
26524, 9113
Predicted Cross Reactivity
Dog, Cow, Horse, Chicken, Rabbit
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
BR-40-750-01 25 mL
DiagNano™ Gold Nanorods, diameter 40 nm, absorption max 750 nm
Sign In for Pricing
View Details 
BR-40-750-02 100 mL
DiagNano™ Gold Nanorods, diameter 40 nm, absorption max 750 nm
Sign In for Pricing
View Details 
