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Phospho-CREM (Ser271 + Ser274) Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity) .

Synonyms

CAMP-responsive element modulator; Inducible cAMP early repressor; ICER; CREM

Gene ID

1390

Modification Site

Ser287 + Ser290

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

Phospho-CREM (Ser271 + Ser274)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic phosphopeptide derived from human CREM around the phosphorylation site of Ser287 + Ser290

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1390

Predicted Cross Reactivity

Human, Pig, Horse, Chicken

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