Phospho-CREM (Ser271 + Ser274) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity) .
Synonyms
CAMP-responsive element modulator; Inducible cAMP early repressor; ICER; CREM
Gene ID
1390
Modification Site
Ser287 + Ser290
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
Phospho-CREM (Ser271 + Ser274)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human CREM around the phosphorylation site of Ser287 + Ser290
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1390
Predicted Cross Reactivity
Human, Pig, Horse, Chicken
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