Histone H4 (Acetyl K8) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008].
Synonyms
Histone H4 Acetyl K8; Histone H4 Acetyl Lys8; Acetyl-Histone H4 Lys8; H4F2; H4FN; HIST1H4; HIST2H4; HISTH4H4; methyl histone H4; histone H4; H4_HUMAN.
Gene ID
121504
Modification Site
K8
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Rat
Target
Histone H4 (Acetyl K8)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic acetylpeptide derived from human Histone H4 around acetylation site of K8
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Acetylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
121504
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
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