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MCT2 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]) .[supplied by OMIM, Feb 2011].

Synonyms

MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7.

Gene ID

9194

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

401-478/478

Target

MCT2

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human SLC16A7

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9194

Available Sizes

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