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PDK2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

Synonyms

PDHK2; Pyruvate dehydrogenase kinase isoform 2; pyruvate dehydrogenase kinase, isozyme 2; Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial; PDK2_HUMAN.

Gene ID

5164

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

315-407/407

Target

PDK2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human PDK2

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

5164

Predicted Cross Reactivity

Mouse, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

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