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NDUFS4 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008].

Synonyms

AQDQ; CI 18 kDa; CI AQDQ; Complex I 18 kDa; Complex I AQDQ; mitochondrial respiratory chain complex I 18 KD subunit; NADH dehydrogenase; NADH ubiquinone oxidoreductase 18 kDa subunit; NDUS4_HUMAN.

Gene ID

4724

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

101-175/175

Target

NDUFS4

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human NDUFS4

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4724

Predicted Cross Reactivity

Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit

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