Chlorphenoxamine
Chlorphenoxamine, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease[1][2][3][4][5].
Product Specifications
CAS Number
77-38-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Filovirus; Histamine Receptor; Parasite; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Chlorphenoxamine.html
Purity
99.20
Solubility
DMSO : ≥ 48 mg/mL
Smiles
CN(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)C)C
Molecular Formula
C18H22ClNO
Molecular Weight
303.83
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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