Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LYK5 Polyclonal Antibody

Product Specifications

Background

Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.

Synonyms

Serologically defined breast cancer antigen NY BR 96; STRAD alpha; Protein kinase LYK5; STE20 related adapter protein; STRAD; STRAA_HUMAN.

Gene ID

92335

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

1-100/431

Target

LYK5

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human LYK5

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-3949R

Gene ID URL

92335

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PE-Cy5 anti-human CD127 (IL-7Rα)
E16FHC127-025 25 Tests

PE-Cy5 anti-human CD127 (IL-7Rα)

Ask
View Details
Rabbit Polyclonal SLP-2 Antibody [Alexa Fluor 488]
NBP2-98494AF488 0.1 mL

Rabbit Polyclonal SLP-2 Antibody [Alexa Fluor 488]

Ask
View Details
Antibody against malaria P.f HRP II
MBS478383-01 1 mg

Antibody against malaria P.f HRP II

Ask
View Details
Antibody against malaria P.f HRP II
MBS478383-02 2 mg

Antibody against malaria P.f HRP II

Ask
View Details
Antibody against malaria P.f HRP II
MBS478383-03 5 mg

Antibody against malaria P.f HRP II

Ask
View Details
Antibody against malaria P.f HRP II
MBS478383-04 10 mg

Antibody against malaria P.f HRP II

Ask
View Details