COX3 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Cytochrome C Oxidase subunits I, II and III form the functional core of the enzyme complex.Defects in Cytochrome C Oxidase subunits III are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency) . Defects in Cytochrome C Oxidase subunits III are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
Synonyms
Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; COIII; COX3; COX-3; COXIII; MT CO3; MTCO3; COX3_HUMAN.
Gene ID
4514
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
25-130/261
Target
COX3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human COX3
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
4514
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Horse, Chicken, Rabbit
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