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PER2 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Synonyms

FASPS; FASPS1; Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2; PER2; KIAA0347

Gene ID

8864

Swiss Prot

O15055

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

751-850/1225

Target

PER2

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human PER2

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8864

Predicted Cross Reactivity

Human

Curated Selection

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