CYP24A1 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.
Synonyms
CP24; HCAI; CYP24; P450-CC24; 1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial; 24-OHase; Vitamin D (3) 24-hydroxylase; Cytochrome P450 24A1; Cytochrome P450-CC24; CYP24A1
Gene ID
1591
Swiss Prot
Q07973
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
351-450/514
Target
CYP24A1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human CYP24A1
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1591
Predicted Cross Reactivity
Dog, Cow, Pig, Horse, Chicken, Rabbit
Curated Selection
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