Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TXNIP Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) .

Synonyms

THIF; VDUP1; HHCPA78; EST01027; Thioredoxin-interacting protein; Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1; TXNIP

Gene ID

10628

Swiss Prot

Q9H3M7

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

101-200/391

Target

TXNIP

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human TXNIP

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-3897R-Cy3

Gene ID URL

10628

Predicted Cross Reactivity

Mouse, Dog, Pig, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Alpha-Bungarotoxin, CF®405S 100ug
#00002-100ug 1x 100 µg

Alpha-Bungarotoxin, CF®405S 100ug

Ask
View Details
CGKII rabbit pAb
ES1966-01 50 µL

CGKII rabbit pAb

Ask
View Details
CGKII rabbit pAb
ES1966-02 100 µL

CGKII rabbit pAb

Ask
View Details
ZNF571 (NM_016536) Human Untagged Clone
SC309729 10 µg

ZNF571 (NM_016536) Human Untagged Clone

Ask
View Details
Yubeinine
MBS3616772-01 5 mg

Yubeinine

Ask
View Details
Yubeinine
MBS3616772-02 10 mg

Yubeinine

Ask
View Details