NOXA2 Polyclonal Antibody, APC-Cy7 Conjugated

This gene encodes neutrophil cytosolic factor 2, the67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

NCF-2; Ncf2; Neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox; neutrophil cytosol factor 2 isoform 1; neutrophil cytosolic factor 2 65kD, chronic granulomatous disease, autosomal 2; NADPH oxidase activator 2; neutrophil cytosol factor 2; 67 kDa neutrophil oxidase factor.