NOXA2 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
This gene encodes neutrophil cytosolic factor 2, the67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
Synonyms
NCF-2; Ncf2; Neutrophil NADPH oxidase factor 2; NOXA2; p67-phox; p67phox; neutrophil cytosol factor 2 isoform 1; neutrophil cytosolic factor 2 65kD, chronic granulomatous disease, autosomal 2; NADPH oxidase activator 2; neutrophil cytosol factor 2; 67 kDa neutrophil oxidase factor.
Gene ID
4688
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-200/526
Target
NOXA2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human NOXA2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4688
Predicted Cross Reactivity
Dog, Cow, Horse, Chicken, Rabbit
Curated Selection
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