NOX2 Polyclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H (+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Synonyms

CGD; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; p22 phagocyte B-cytochrome; CYBB

Gene ID

1536

Swiss Prot

P04839

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

501-570/570

Target

NOX2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human NOX2/gp91phox

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1536

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-24155AF700 0.1 mL

Rabbit Monoclonal CD31/PECAM-1 Antibody (C31/8593R) [Alexa Fluor 700]

Ask

View Details

406804-01 50 µL

NFKBIE (NF-kappa-B Inhibitor Epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon, NFKBIE, IKBE)

Ask

View Details

406804-02 100 µL

NFKBIE (NF-kappa-B Inhibitor Epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon, NFKBIE, IKBE)

Ask

View Details

MBS1474280-01 0.02 mg (E-Coli)

Recombinant Xenopus laevis AN1-type zinc finger protein 3 homolog (zfand3)

Ask

View Details

MBS1474280-02 0.1 mg (E-Coli)

Recombinant Xenopus laevis AN1-type zinc finger protein 3 homolog (zfand3)

Ask

View Details

MBS1474280-03 0.02 mg (Yeast)

Recombinant Xenopus laevis AN1-type zinc finger protein 3 homolog (zfand3)

Ask

View Details