Phospho-Crkl (Tyr251) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.
Synonyms
Crk-like protein; CRKL
Gene ID
1399
Swiss Prot
P46109
Modification Site
Tyr251
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Crkl (Tyr251)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic phosphopeptide derived from human Crkl around the phosphorylation site of Tyr251 [CA (p-Y) D]
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1399
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6479479-01 0.1 mL
Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 405)
Ask
View Details MBS6479479-02 5x 0.1 mL
Haptoglobin (HP, BP, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP2ALPHA2, HPA1S, MGC111141) (MaxLight 405)
Ask
View Details