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Phospho-Claudin 6 (Tyr219) Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Claudin 6 is a multipass transmembrane protein in the Claudin family. Claudin 6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Claudin 6 is also a global marker of definitive endoderm. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.

Synonyms

Claudin6; CLDN 6; CLDN6; Skullin 2; CLD6_HUMAN.

Gene ID

9074

Modification Site

Tyr219

Cellular Locus

Cell membrane

Host

Rabbit

Target

Phospho-Claudin 6 (Tyr219)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic phosphopeptide derived from human Claudin 6 around the phosphorylation site of Tyr219

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9074

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Sheep, Horse, Rabbit

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