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AF10 Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t (10;11) (p12; q23) with MLL/HRX. The result is a rogue activator protein.A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t (10;11) (p13; q14) with PICALM.

Synonyms

AF 10; AF10; AF10_HUMAN; ALL 1 fused gene from chromosome 10; ALL1 fused gene from chromosome 10; ALL1-fused gene from chromosome 10 protein; MLLT 10; MLLT10; Myeloid/lymphoid or mixed lineage leukemia trithorax homolog Drosophila translocated to 10; Myeloid/lymphoid or mixed lineage leukemia translocated to 10; Protein AF 10; Protein AF-10; Protein AF10; Type I AF10 protein.

Gene ID

8028

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

151-250/1027

Target

AF10

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human AF10/MLLT10

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8028

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit

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