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DIO2 Polyclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) . It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.

Synonyms

5DII; D2; Deiodinase, iodothyronine, type II; DIOII; ITDI2; SelY; Thyroxine deiodinase, type II; TXDI2; Type 2 DI; Type II 5' deiodinase; Type II iodothyronine deiodinase.

Gene ID

1734

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

101-200/273

Target

DIO2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human DIO2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1734

Predicted Cross Reactivity

Dog, Cow, Sheep, Pig, Horse, Rabbit

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