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F11R/JAM-A/CD321 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Synonyms

JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; F11R; UNQ264/PRO301

Gene ID

50848

Swiss Prot

Q9Y624

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-150/299

Target

F11R/JAM-A/CD321

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

50848

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig

Available Sizes

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