Plexin A2 Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Plexin A2 is a coreceptor for SEMA3A and is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. This coreceptor plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin in which the plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Synonyms
PlexinA2; PLXA2; PLXNA2; Semaphorin receptor OCT.
Gene ID
5362
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
1251-1400/1894
Target
Plexin A2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human Plexin A2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5362
Predicted Cross Reactivity
Human, Mouse, Rat
Curated Selection
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