Tbx21 Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG) . Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008].
Synonyms
T bet; T box 21; T box expressed in T cells; T box protein 21; T box transcription factor TBX21; T cell specic T box transcription factor; T cell specic T box transcription factor T bet; T PET; TBET; TBLYM; TBX 21; TBX21; TPET; Transcription factor TBLYM; TBX21_HUMAN; T-box transcription factor TBX21; T-box protein 21; T-cell-specic T-box transcription factor T-bet; Transcription factor TBLYM.
Gene ID
30009
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Tbx21
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human Tbx21
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
30009
Curated Selection
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