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Tbx21 Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG) . Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008].

Synonyms

T bet; T box 21; T box expressed in T cells; T box protein 21; T box transcription factor TBX21; T cell specic T box transcription factor; T cell specic T box transcription factor T bet; T PET; TBET; TBLYM; TBX 21; TBX21; TPET; Transcription factor TBLYM; TBX21_HUMAN; T-box transcription factor TBX21; T-box protein 21; T-cell-specic T-box transcription factor T-bet; Transcription factor TBLYM.

Gene ID

30009

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Tbx21

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human Tbx21

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

30009

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