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GRIM19 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.

Synonyms

CDA016; Cell death regulatory protein; Cell death regulatory protein GRIM-19; CGI-39; CGI39 protein; CI-B16.6; GRIM-19; GRIM 19; Complex I-B16.6; Gene associated with retinoic and N-induced mortality 19 protein; Gene associated with retinoic and interferon-induced mortality 19 protein; Gene associated with retinoic interferon induced mortality 19 protein; GRIM-19; NADH dehydrogenase ubiquinone 1 alpha subcomplex, 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; NADH ubiquinone oxidoreductase B16.6 subunit; Ndufa13.

Gene ID

51079

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

51-144/144

Target

GRIM19

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human GRIM19

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51079

Predicted Cross Reactivity

Rat, Pig, Horse

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