GRIM19 Polyclonal Antibody
Product Specifications
Background
A novel gene, Genes associated with Retinoid IFN induced Mortality (GRIM) GRIM19 gene was identified. Antisense expression of GRIM19 confers a strong resistance against IFN/RA induced death by reducing the intracellular levels of GRIM19 protein. Overexpression of GRIM19 enhances cell death in response to IFN/RA. GRIM19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM19 is a novel cell death regulatory molecule.
Synonyms
CDA016; Cell death regulatory protein; Cell death regulatory protein GRIM-19; CGI-39; CGI39 protein; CI-B16.6; GRIM-19; GRIM 19; Complex I-B16.6; Gene associated with retinoic and N-induced mortality 19 protein; Gene associated with retinoic and interferon-induced mortality 19 protein; Gene associated with retinoic interferon induced mortality 19 protein; GRIM-19; NADH dehydrogenase ubiquinone 1 alpha subcomplex, 13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; NADH ubiquinone oxidoreductase B16.6 subunit; Ndufa13.
Gene ID
51079
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
51-144/144
Target
GRIM19
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GRIM19
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
51079
Predicted Cross Reactivity
Rat, Pig, Horse
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