DTNB Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.
Synonyms
Dystrobrevin beta; DTN-B; Beta-dystrobrevin; DTNB
Gene ID
1838
Swiss Prot
O60941
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Rat
Immunogen
261-370/627
Target
DTNB
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human DTNB
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody may cross-react with DTNA based upon a 75% sequence similarity across the immunogen sequence range.
Gene ID URL
1838
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Horse, Chicken, Rabbit
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