DTNB Polyclonal Antibody

Product Specifications

Background

Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.

Synonyms

Dystrobrevin beta; DTN-B; Beta-dystrobrevin; DTNB

Gene ID

1838

Swiss Prot

O60941

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Rat

Immunogen

261-370/627

Target

DTNB

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human DTNB

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Specificity

This antibody may cross-react with DTNA based upon a 75% sequence similarity across the immunogen sequence range.

Gene ID URL

1838

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Horse, Chicken, Rabbit

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