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PLCG 2 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Synonyms

FCAS3; APLAID; PLC-IV; PLC-gamma-2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; Phospholipase C-gamma-2; PLCG2

Gene ID

5336

Swiss Prot

P16885

Cellular Locus

Cytoplasm, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

645-750/1265

Target

PLCG 2

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human PLCG 2/PLC gamma 2

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody may also recognize PLCG1 due to sequence similarity.

Gene ID URL

5336

Predicted Cross Reactivity

Mouse, Dog, Cow, Pig, Horse, Rabbit

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