Phospho-CDK2 (Thr160) Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) . Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
Synonyms
P-CDH2 Thr160; CDH2 Thr160; CDH2 T160; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2_HUMAN.
Gene ID
1017
Modification Site
Thr160
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-CDK2 (Thr160)
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic phosphopeptide derived from human CDK2 around the phosphorylation site of Thr160 [TY (p-T) HE]
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1017
Curated Selection
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