Phospho-YAP1 (Tyr407) Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to the SH3 domain of the YES kinase (a Src protein kinase) . More recently it has been identified as a candidate oncogene that promotes tumorigenesis in many different types of cancer.

Synonyms

65 kDa Yes associated protein; YAp 1; YAp-1; YAP 65; YAP; YAP2; YAP65; Yes associated protein 1 65kDa; Yes associated protein 1; Yes associated protein 2; YKI.

Gene ID

10413

Modification Site

Tyr407

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-YAP1 (Tyr407)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic phosphopeptide derived from human YAP around the phosphorylation site of Tyr407

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10413

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

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