Phospho-VEGF receptor 2 (Tyr1059) Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
Synonyms
VEGFR2Tyr1059; VEGFR2Y1059; p-VEGFR2Tyr1059; p-VEGFR2Y1059; CD309; CD309 antigen; Fetal liver kinase 1; FLK-1; FLK1; KDR; Kinase insert domain receptor a type III receptor tyrosine kinase; Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN.
Gene ID
3791
Modification Site
Tyr1059
Cellular Locus
Cytoplasm, Nucleus, Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Others
Target
Phospho-VEGF receptor 2 (Tyr1059)
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic phosphopeptide derived from human VEGF receptor 2 around the phosphorylation site of Tyr1059
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3791
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Curated Selection
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