Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-Stat2 (Tyr690) Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Synonyms

P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2

Gene ID

6773

Swiss Prot

P52630

Modification Site

Tyr690

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-Stat2 (Tyr690)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.

Gene ID URL

6773

Predicted Cross Reactivity

Human, Rat, Dog, Horse

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Succinic Acid-1,4-13C2
TRC-S688768-5MG 5 mg

Succinic Acid-1,4-13C2

Sign In for Pricing
View Details
Von Willebrand Factor (VWF) Mouse Monoclonal Antibody [Clone ID: 3E2D10]
AM50326PU-T 20 µg

Von Willebrand Factor (VWF) Mouse Monoclonal Antibody [Clone ID: 3E2D10]

Sign In for Pricing
View Details
FNIP1 Antibody
SPC-718D 100 µg

FNIP1 Antibody

Sign In for Pricing
View Details
Hexyl Chloroformate
TRC-H295700-1G 1 g

Hexyl Chloroformate

Sign In for Pricing
View Details
Human Arylsulfatase B (ARSB) ELISA Kit
RDR-ARSB-Hu-01 96 Tests

Human Arylsulfatase B (ARSB) ELISA Kit

Sign In for Pricing
View Details
Human Arylsulfatase B (ARSB) ELISA Kit
RDR-ARSB-Hu-02 48 Tests

Human Arylsulfatase B (ARSB) ELISA Kit

Sign In for Pricing
View Details