Phospho-SGK1 (Ser422) Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

Synonyms

SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1; SGK1

Gene ID

6446

Swiss Prot

O00141

Modification Site

Ser422

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-SGK1 (Ser422)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic phosphopeptide derived from human SGK1 around the phosphorylation site of Ser422

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6446

Predicted Cross Reactivity

Dog, Pig, Horse, Rabbit

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SI005589A 1 Each

Human FCGR2B Pre-designed siRNA Set A

Ask

View Details

352368 100 µg

MAP1LC3A, NT (LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3 Autophagy-Related Protein LC3 A)

Ask

View Details

030235 100 µL

FN1 (Fibronectin)

Ask

View Details

HY-R00423A-01 5 nmol

Hsa-miR-208b-3p agomir

Ask

View Details

HY-R00423A-02 20 nmol

Hsa-miR-208b-3p agomir

Ask

View Details