Phospho-PLCG1 (Tyr783) Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Synonyms

PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1

Gene ID

5335

Swiss Prot

P19174

Modification Site

Tyr783

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Target

Phospho-PLCG1 (Tyr783)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous across the listed species.

Gene ID URL

5335

Predicted Cross Reactivity

Human, Mouse, Dog, Pig, Horse, Chicken

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TL708844V 500 µL Each

Ccdc89 Rat shRNA Lentiviral Particle (Locus ID 293107)

Ask

View Details

NBP2-98496PE 0.1 mL

Rabbit Polyclonal SYT11 Antibody [PE]

Ask

View Details

MBS6124192-01 0.1 mL

Fibronectin (Cold insoluble globulin, CIG, FINC, FN1, FNZ, GFND, GFND2, LETS, Migration Stimulating Factor, MSF, Ugl-Y3) (AP)

Ask

View Details

MBS6124192-02 5x 0.1 mL

Fibronectin (Cold insoluble globulin, CIG, FINC, FN1, FNZ, GFND, GFND2, LETS, Migration Stimulating Factor, MSF, Ugl-Y3) (AP)

Ask

View Details

RD78423A-01 20 µL

ATG4B Polyclonal Antibody

Ask

View Details

RD78423A-02 60 μL

ATG4B Polyclonal Antibody

Ask

View Details