Phospho-PLCG 2 (Tyr759) Polyclonal Antibody, PerCP Conjugated
Product Specifications
Background
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
Synonyms
PLC 2; PLC gamma 2; PLC IV; PLCG2; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2; EC 3.1.4.11; Phosphoinositide phospholipase C; Phospholipase C gamma 2; Phospholipase C, gamma 2 phosphatidylinositol specic; PLCG2_HUMAN.
Gene ID
5336
Modification Site
Tyr759
Cellular Locus
Cytoplasm, Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-PLCG 2 (Tyr759)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PerCP
Source
KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr759
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5336
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
OM619723 96 Strip Well
Bovine Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1) ELISA Kit
Ask
View Details B2553-36 100 µg
Bone Morphogenetic Protein 9 (BMP9, Growth and Differentiation Factor 2, GDF2)
Ask
View Details 
GTR15382162 1 Vial
Lentiviral human BAIAP2L1 sgRNA gene knockout kit - Lentiviral human BAIAP2L1 sgRNA gene knockout kit (100)
Ask
View Details