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Phospho-Nur77 (Ser351) Polyclonal Antibody

Product Specifications

Background

NUR77 is a member of the steroid/thyroid hormone receptor superfamily. The gene for NUR77 is induced rapidly by androgens/growth factors and may have functions related to cell proliferation, differentiation and apoptosis. It has been demonstrated that mouse NUR77 is necessary for induced apoptosis in T-cell hybridomas and can also be induced during early mitogenesis. NUR77 is a phosphoprotein and its size ranges from 67 kDa to 88 kDa, depending on post-translational modifications.

Synonyms

NR4A1phospho S351; GFRP 1; GFRP; GFRP1; Growth factor inducible nuclear protein N10; Growth Factor Inducible Nuclear Protein NP10; Growth Factor Response Protein 1; Hbr1; HMR; Hormone Receptor; MGC9485; N10; N10 nuclear protein; NAK 1; NAK1; NGFIB; NP 10; NP10; NR4A1; Nuclear hormone receptor NUR/77; Nuclear Hormone Receptor TR3; Nuclear Receptor Subfamily 4 Group A Member 1; NUR77; Orphan nuclear receptor HMR; Orphan nuclear receptor NR4A1; ST 59; ST59; Steroid receptor TR3; TR 3; TR3; TR3 orphan receptor; Early response protein NAK1.

Gene ID

3164

Modification Site

Ser351

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-Nur77 (Ser351)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human Nur77 around the phosphorylation site of Ser351

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3164

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Horse, Chicken, Rabbit

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